Moghaddam introduces LTP as a hypothesis about the biological basis of memory. He reviews a few earlier hypotheses including the possibility that memory is stored in RNA molecules. In the lecture period I mentioned a few hypotheses that have been considered since the time that Moghaddam wrote his book. This past week the neuroscience world was abuzz with evidence that the answer does lie at the molecule level, but the type of molecule is calcium/calmodulin dependent protein kinase, or CaMKII for short. Read the full story here.